Some Drano products carry a “septic safe” claim on the label. This is misleading. The Environmental Protection Agency (EPA) does not regulate the term “septic safe” for drain cleaners. Manufacturers may test short-term effects in ideal lab conditions, but real-world use – especially repeated use – harm your system.
According to S.C. Johnson (the makers of Drano), their products are safe for plastic and metal pipes and "will not harm" a septic system when used as directed. They argue that the chemical becomes diluted enough by the time it reaches the tank that it won't cause a total bacterial die-off. is drano safe for septic tanks
Instead of chemical drain cleaners, try these septic-safe options: Some Drano products carry a “septic safe” claim