Dylan Harper (Mila Kunis) is a headhunter, while Jamie Rellis (Justin Timberlake) is an executive for a publishing company. They meet on a first date and decide to have a no-strings-attached relationship, with a set of rules to keep things simple: no dating, no relationships, and no emotions. As they continue to hook up, they start to develop feelings for each other, which complicates their initial agreement.