Sony Pictures has secured the rights, with the film scheduled for theatrical release in . In a surprising move for a horror franchise, it has also been reported that a sequel—tentatively titled 28 Years Later Part II —is already planned, indicating that Garland and Boyle view this not just as a one-off sequel, but as the beginning of a new chapter in the saga.

For years, fans have clamored for a sequel to 28 Weeks Later (2007). While the second film was a commercial success, it received mixed critical reception compared to its predecessor. Talks of a third film—often jokingly referred to as 28 Months Later —stalled for over a decade.