Disadvantage: Some synthetic surfactants (especially SLS) can be more irritating than true soap for certain individuals; environmental persistence of some syndets (e.g., SLES with 1,4-dioxane residues) is a concern.
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While other "Soaper alternatives" focus on better memory or smarter models, changes the structure of the interaction. It turns a choose-your-own-adventure book into a multiverse simulator. environmental persistence of some syndets (e.g.